NUXI problem /nuk'see pro'bl*m/ n. Refers to the problem of transferring data between machines with differing byte-order. The string `UNIX' might look like `NUXI' on a machine with a different `byte sex' (e.g., when transferring data from a little-endian to a big-endian, or vice-versa). See also middle-endian, swab, and bytesexual.